Shisiedo Ultimune Power Infusing Serum

This 5th-generation Ultimune Serum works at the root of skin aging—gently removing aged cells to restore youthful resilience and radiance.

Key ingredients
Skin immunity “Memory T Cells” memorize aged cells. By detecting & targeting precisely, Memory T Cells effectively attack and diminish aged cells.
Exclusive Power Fermented Camellia+ : boosts power of Memory T Cells, diminishing aged cells before new aging sign appears. Original Japanese bio-fermentation technology based on Japanese sake, for 3.4X boost of amino acids in camellia seeds.

Camellia Seed extract: generates Langerhans cells by promoting to recruit Langerhans cells precursors, supports collagen production by Boosting fibroblast proliferation and enhances skin’s antioxidant power (SOD activity) to counteract increased oxidative damage due to external stressors.

Camellia Leaf extract: supports the skin barrier by suppressing inflammation caused by sebum.

- Newly reformulated in 2025
- Non-comedogenic
- Made in Japan